While the analysis on most supplements for joint ache is combined, and the FDA doesn’t regulate supplements, fish oil, glucosamine, and chondroitin are among these which will help handle it. Dozens of supplements claim to treat joint pain, in addition to typical ache relievers like acetaminophen and ibuprofen, but which of them truly work? Here, we have a look at 9 options and what existing analysis says about them. Supplements should not Food and Drug Administration (FDA) authorized. Speak together with your doctor and a registered dietitian earlier than taking any and solely buy from trusted sellers. Turmeric is considered one of the most well-liked supplements for treating ache, together with joint ache brought on by osteoarthritis (OA). Its ache-relieving results are attributed to a chemical compound in turmeric called curcumin. Curcumin might have anti-inflammatory effects. Although research on turmeric for joint ache is limited, a 2021 analysis overview of 10 studies discovered that supplementation with turmeric or curcumin extract improves knee OA joint pain in comparison with a placebo.

More research is required on the dosing, better concentration daily frequency, and formulation of those supplements. But 500 to 1,500 milligrams (mg) day by day for 3 months has proven promising leads to analysis. A 4-month, randomized examine revealed in 2020 found that fish oil supplements significantly reduce OA-particular pain and enhance properly-being. But more research is required. The National Institutes of mind guard brain health supplement (NIH) recommends 1,600 mg daily for males and 1,a hundred mg each day for girls. Glucosamine is a natural element of cartilage, a substance that prevents bones from rubbing towards one another and inflicting ache and inflammation. It may also help prevent the cartilage breakdown that can occur with arthritis. Many joint pain supplements comprise glucosamine (as either glucosamine sulfate or glucosamine hydrochloride), one of the crucial properly-studied supplements for osteoarthritis. Despite this analysis, findings have been inconsistent. A 2018 research evaluate of 29 studies cited some research that discovered glucosamine improved knee OA pain and others that discovered little to no improvement in joint pain.

Glucosamine sulfate is usually taken as soon as every day in a dose of 1,500 mg. If this upsets your stomach, unfold it out over three doses of 500 mg every. Like glucosamine, chondroitin is a building block of cartilage. It might also assist stop cartilage breakdown from OA. Many research have discovered that chondroitin might cut back joint ache, stiffness, and inflammation in people with OA. Chondroitin sulfate may gradual the progression of OA by limiting joint space narrowing. Joint supplements typically mix chondroitin with glucosamine. But it’s still unclear if taking a mix supplement is any better concentration daily than taking one or the other alone. A 2018 research overview discovered that glucosamine or chondroitin supplementation diminished joint ache when taken separately and not in combination. Chondroitin suggestions can vary from 800 mg to 1,200 mg. You might take this as a single dose or in four hundred mg doses 2 to three occasions.

Your liver naturally produces S-adenosyl-L-methionine (Same) from an amino acid known as methionine. Current research on the advantage of Same for joint ache is missing, and the present research is inconsistent. A 2009 clinical trial of Korean contributors discovered that same didn’t relieve pain greater than another treatment after 8 weeks. In previous research, Same was often taken in doses of 800 mg each day. It might take some time to note the results. Boswellia, or better concentration daily Indian frankincense, is usually used to treat arthritis pain. Its extract contains chemicals called Boswellia acids, which may have anti-inflammatory and anti-arthritic effects. A 2020 animal research found that Boswellic acids relieve OA pain and protect cartilage. More human analysis is required to further help its use for joint pain. The NIH recommends 250 to 500 mg of Boswellia serrata 2 or 3 times every day. Avocado-soybean unsaponifiables (ASUs) refer to an extract from avocado and soybean oils that may help prevent cartilage breakdown and repair it. A 2018 study in rats found that remedy with ASU lessened joint ache.

These findings point to the use of ASUs for joint inflammation and ache associated with finish stage OA, but more analysis in people is needed. 300 mg of ASUs daily may be a superb starting dose. Devil’s claw, also known as harpagophytum, accommodates a chemical referred to as harpogoside, which may have anti-arthritic and anti-osteoporosis effects. A 2022 mouse mannequin examine discovered that it might sluggish bone erosion from inflammatory arthritis. An older study published in 2000 discovered devil’s claw worked about as well as an anti-inflammatory drug referred to as diacerein. However, recent human research on this supplement for osteoarthritis is lacking, so extra prime quality studies are essential. It’s recommended to take 500 to 1,500 mg of devil’s claw dried root capsules three occasions daily. Methylsulfonylmethane (MSM) could have anti-inflammatory results. In a 2023 examine of 88 contributors in Japan with mild knee joint pain, 12 weeks of MSM supplementation led to significantly improved circumstances. Specifically, the research found that taking 5 200 mg MSM tablets with breakfast and dinner improved knee and total well-being compared to a placebo.